There are numerous ways to commute in and out of Makati.
Two of Metro Manila’s main roads lead you to Makati. Epifanio De los Santos Avenue (EDSA) passes along the southeast part of Makati and connects the city with Mandaluyong City and Pasay City. The South Luzon Expressway (SLEX) runs through the western part of Makati and connects the city with Manila to the north and with southern Metro Manila. The Skyway, an elevated highway built on top of SLEX, provides residents from southern Metro Manila a speedy alternative to reach Makati.
Other major roads in Makati include Sen. Gil Puyat Avenue (also known as Buendia), which connects with EDSA and SLEX in the north; Ayala Avenue, a main street that runs through the Central Business District; and Makati Avenue, which connects Ayala Avenue with Buendia Avenue and also extends north to cross the Pasig River to Mandaluyong City.
Buses with routes along EDSA pass through the Makati Central Business District daily. Note the separate loading and unloading zones along Ayala Avenue.
POINT-TO-POINT BUS SERVICE
Point-to-Point Bus Service is available within Metro Manila to and from malls in the North (TriNoma), South (Alabang Town Center), and Ortigas (SM Megamall and Robinsons Galleria).
More info here: http://www.officialgazette.gov.ph/2016/05/03/p2p-bus-services/
AYALA FORT BUS
The Ayala Fort Bus serves as a link between the Makati Central Business District and Bonifacio Global City. It mainly traverses McKinley Road and the following roads in Bonifacio Global City: McKinley Parkway, 5th Avenue, 26th Street, Rizal Drive, and 32nd Street.
The Metro Rail Transit (MRT) is a quick and inexpensive way to get into the city. Also known as the “Blue Line” or “Line 3,” the MRT is composed of 13 stations stretched across EDSA. Its operating hours are from 5:00 AM – 1:00 AM during weekdays, and 5:30 AM – 10:30 PM during weekends.
The MRT elevated train has four stations along the main thoroughfare Epifanio De los Santos Avenue (EDSA) that can bring you to Makati. These are the Guadalupe, Buendia, Ayala and Magallanes stations. Getting off at the Ayala Station will set you in the middle of the Ayala Center, a complex of shopping malls and restaurants.
The cost of an MRT ticket ranges from 11 to 14 pesos. The Manila Train Guide is a useful app that has a map and tips on how to use the train system.